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\pageno=1
\hsize 7truein
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 Ernst, C.; Sumners, D. W. A calculus for rational tangles: applications to 
DNA recombination. Math. Proc. Cambridge Philos. Soc. 108 (1990), no. 3, 
489--515. 

Vazquez, Mariel; Sumners, De Witt; Tangle analysis 
of Gin site-specific recombination. Math. Proc. Cambridge Philos. Soc. 136 
(2004), no. 3, 565--582.

Darcy, Isabel K. Biological distances on DNA knots and links: applications to 
XER recombination. Knots in Hellas '98, Vol. 2 (Delphi). J. Knot Theory 
Ramifications 10 (2001), no. 2, 269--294.

math.GT/0501173;
Title: Classification of Tangle Solutions for Integrases, A Protein Family 
that Changes DNA Topology;
Authors: Dorothy Buck, Cynthia Verjovsky Marcotte

math.GT/0412467;
Title: Tangle Solutions for a Family of DNA-Rearranging Proteins;
Authors: Dorothy Buck, Cynthia Verjovsky Marcotte


Useful facts about tangles:
\v

p. 491:

The tangle corresponding to ${a_1 \over b_1}$ is the same as
the
tangle corresponding to ${a_2 \over b_2}$ if and only if ${a_1 \over b_1}
= {a_2 \over b_2}$ 
%% \cite{Conway, BZ, Mont19}. 
\v
\eject
Parity:
\vfill
\vfill


In order to determine the parity of ${a \over b}$, the Euler bracket function
will be used. Let $E[x_1,..., x_n]$ be the Euler bracket function which
equals the sum of products of the $x_i$'s where zero or more disjoint
pairs of consecutive $x_i$'s are omitted \cite{Roberts}.  If $n = 0$
then $E[x_1,..., x_n] = E[] = 1$. If $n < 0$ define $E[x_1,..., x_n] =
0$.   Let $[x_n, ..., x_1]$ denote the continued fraction $x_n + {1 \over
x_{n-1} + {1 \over ... + { 1 \over x_1}}}$, the fraction corresponding
to the tangle $(x_1, ..., x_n)$.
The following useful facts for $n \geq 1$ can be found in
%%\cite{Roberts}:

\hskip 10pt 1.) $E[x_1,..., x_n] = x_1 E[x_2,..., x_n] + E[x_3,...,
x_n]$.

\hskip 10pt 2.) $[x_n, ..., x_1]$ = $E[x_1, ...,
x_n]/E[x_1, ..., x_{n-1}]$.

\hskip 10pt 3.) Let $a = E[x_1, ..., x_n], b = E[x_1, ...,
x_{n-1}]$.  If $y = (-1)^{n+1}E[x_2, ..., x_{n-1}]$

\hskip 27pt and
$x =
(-1)^{n+1}E[x_2, ..., x_n]$, then $bx - ay = 1$.

\eject


%%\begin{lemma}{\it 
Lemma:  If $a$ is even, then the tangle ${a \over b}$ has
parity 0. If $a$ is odd, then if $b$ is odd, the tangle ${a \over b}$ has  
parity 1 and if $b$ is even, the tangle ${a \over b}$ has parity
$\infty$. 
%% \label{t-par1} } 
%%\end{lemma}

{\bf Proof.} Induction on n noting that if ${a \over b} = [x_n, ...,
x_1]$, then $a = E[x_1, ..., x_n]$ and $b =
E[x_1, ..., x_{n-1}]$ \qed\kern0.8pt . 
 


 Both $N(a/b)$ and $D(a/b)$ are 4-plats. The knot/link $N(a/b)$
is
the 4-plat $S(a, -b)$. The knot/link $D(a/b)$ is the 4-plat $S(b, a)$.
\v

p. 493:

%% $N((c_1, ..., c_n)) = N((c_n, ..., c_1)) = N((c_1, ..., c_n - 1, 1)) $

%% \rightline{$= N((1, c_1 - 1, ..., c_n))$}



The 4-plats $N(a_1/b_1)$ and $N(a_2/b_2)$, $a_i \geq 0$, are
are
the same if and only if $a_1 = a_2$ and $b_1b_2^{\pm 1} \cong 1$ (mod
$a_1$). 
%% \cite{Shubert21, BZ, KG}.

i.e. $b_1 = b_2$ (mod $a_1$) or
$b_1 b_2$ = 1 (mod $a_1$) 

or equivalently, 
 $b_1 = b_2$ (mod $a_1$) or
$b_1 = b_2^{-1}$ (mod $a_1$) 

%% \v The mirror image of $N({a \over b})$ is $N(-{a \over b})$

%% $N({a \over b})$ is achiral if and only if $b^2 \cong -1$ (mod $a$) or $2b = 1$ (mod $a$).

p. 494:

 {Lemma 2.1:  $N({a_1 \over b_1} + {a_2 \over b_2}) = N({a_1b_2 +
a_2b_1 \over a_1b_2' +a_2'b_1})$ where $a_2'b_2 - a_2b_2' = 1$ [5].
\v


p. 496:  

%%\begin{lemma}

Thm 2.2:  If $N({j \over p} + {f \over g}) = N({a \over b})$, then ${f \over
g} = {da - jb' \over pb' - qa}$ for some integers $d$, $q$, and $b'$ such
that $pd - qj = 1$, $b'b^{\pm 1} = 1$ mod $a$.

%%\label{t-solve}
%%\end{lemma}

{\bf Proof.} $N({j \over p} + {f \over g}) = N({jg + pf \over
dg + qf}) = N({a \over b})$ where $d$ and $q$ are any integers such
that $pd - qj = 1$.  Since ${f \over g} = {-f \over -g}$ and
$N({j \over p} + {-f \over -g}) = N(
{-jg - pf \over -dg - qf}) =
N({jg + pf \over
dg + qf})$, $jg + pf$ will be taken to have the
same sign as $a$. Thus $jg + pf = a$ and $dg + qf = b'$ where
$b'b^{\pm 1} = 1 ~mod~ a$.
 Multiplying the first equation by $d$, the second equation by $j$,
and solving for $f$ results in $f = (pd - qj)f = da - jb'$.
 Multiplying the first equation by $q$, the second equation by $p$,
and solving for $g$ results in $g = (pd - qj)g = pb' - qa$
\qed\kern0.8pt .

Alternate proof use:

%%\begin{lemma} 
{\it
$N(A \circ (c_1, ..., c_n) + B) = N(A + B \circ (c_n, ..., c_1))$
if $A$ or $B$ is rational, $n$ odd.
}
%% \label{t-circle}
%%\end{lemma}




$N(A + C) = N(C + A)$

 $A + C \not= C + A$


%% ${a_1 \over b_1} + {a_2 \over b_2} \not=$ a rational tangle unless either
%% $b_1 = \pm 1$ or $b_2 = \pm 1$. \v

%% ${a \over b} + t = {a + bt \over b} $

p. 498:


Corollary 2.3: Let $B, E$ be distinct rational tangles, Then there are at 
most two 
distinct rational solutions to the system of tangle equations 
$N(X + B) = N({a \over b})$
$N(X + E) = N({z \over v})$

A tangle C is locally unknotted if every 3-ball which intersects the
arcs of C in exactly 2 points contains an unknotted spanning arc.  A
tangle is locally knotted if  not locally unknotted.  A
tangle is prime if it is neither rational nor locally knotted.


Lemma 2.4:  If $R$ is rational, then $R + R$ is locally unknotted.  If $R + 
R$ is rational, then $R$ is integral.  If $R$ is not integral and does not 
have 
parity infinity, then $R + R$ is prime

\v 

If A is a prime tangle and C is locally unknotted
and not the $\infty$-tangle, then 
A + C is a prime tangle  [9][10].


 $D(A + C) = D(A) \# D(C)$.

  
%% $N({a_1 \over b_1} + ... + {a_n \over b_n})$ is a Montesinos knot which is
%% not a 4-plat unless at most two of the tangles ${a_i \over b_i}$ are
%% non-integral.


p. 499:

 Lemma 3.1:  N(A + C) = 4-plat implies at least one of A or C is
rational or
locally knotted [8][9].
\v
  

}



\th{Cyclic Surgery Theorem [CGLS]:}{ Suppose that M is not a Seifert
fibered space.  If $\pi_1(M(r))$ and $\pi_1(M(s))$ are cyclic, then  
$|i(r,s)| \leq1$.  Hence there are at most three slopes r such that
$\pi_1(M(r))$ is cyclic.  }


\eject

 $R$ is a rational tangle if and only if its double branch 
cover is a solid torus.

 $M$ a ambient isotopic to a sum of rational tangles if and 
only if its double branch cover is a Seifert fiber space with orbit 
surface a disk and $n > 0$ exceptional fibers [11].

Lemmas 3.1 - 3.7 are used to prove that the double branch cover of $X$ is a 
torus and hence $X$ is a rational tangle.

We will instead use the following to solve equations where $X$ is a 
generalized M-tangle.  This includes the case when $X$ is rational.

%%\begin{theorem}(Ernst, \cite{E1})
{\it
 If $N(U + {f_1 \over g_1}) = N({a \over b})$
and $N(U +
{f_2 \over g_2}) = N({z \over v})$ and if $|t| > 1$, then $U$ is
a generalized M-tangle
or equivalently, $U = A \circ C$ where $A$
is a finite sum of rational tangles and $C$ is a rational tangle.
}


%%\begin{theorem}
{\it
$N(U + {0 \over 1}) = N({a \over b})$ and $N(U + {t \over w})
= N({z \over v})$ where $N({a \over b})$ and $N({z \over v})$ are unoriented
4-plats and $U$ is a generalized M-tangle if and only
if the following hold:

(a) If $w \not\cong \pm 1$ mod $t$, then there exists an integer, $b'$ such
that
$b'b^{\pm1} =
1$ mod $a$, and for any integers $x$ and $y$ such that $b'x - ay = 1$,

%%\begin{equation}
\centerline{$N({z \over v}) = N({tb'+ wa \over ty+wx})$}
%% \label{e-wnot1}
%%\end{equation}

In this case, $U = {a \over b'}$ for all $b'$ satisfying the above.

(b) If $w \cong \pm 1$ mod $t$, then there exists relatively prime
integers, $p$ and $q$, where $p$ may be chosen to be positive,
such that

%%\begin{equation}
\centerline{$N\big({z \over v}\big) =
 N\big( {tp(pb - qa) \pm a \over tq(pb - qa) \pm b}\big)$}
%% \label{e-w1}
%%\end{equation}


In this case, the solutions for $U$ are
  $({da - jb \over pb - qa} + {j \over p})\circ(h, 0)$
  and  $({j \over p} + {da - jb \over pb - qa})\circ(h, 0)$,
 for all $p, q$ satisfying the above, $d$ and $j$ are any integers
such that $~pd - qj =
1$, and $h = {-w \pm 1 \over t}$ where the $\pm$ sign agrees with
that in (\ref{e-w1}) (note, the choice of $j$ and $d$ such that
$pd - qj = 1$ has no effect on $U$).  }
 %% \label{t-un}
%%\end{theorem}


%% begin{corollary}{\it 
 Suppose $bx - ay = 1$, $N(U + {0 \over 1}) = N({a
\over b})$ and $N(U + {t \over w}) = N({z \over v})$ where $N({a \over b})$
and $N({z \over v})$ are unoriented 4-plats.  If $w \not\cong \pm 1$ or if
$U$ is rational, then ${t \over w} = {xz - av' \over bv' - yz - kt}$ and $U =
{a \over b + ka}$ OR ${t \over w} = {bz - av' \over xv' - yz - kt}$ and $U =
{a \over x + ka}$ where $v'$ is any integer such that $v'v^{\pm 1} = 1$ mod
$z$.  If $w \cong \pm 1$ mod $t$, then $t$ divides $z \mp a$.


bottom of p. 502:
\vskip -5pt
{\bf Theorem 7 [19] }
{If $N(U + {f_1 \over g_1}) =$ unknot and $N(U + {f_2 \over g_2}) =
N(2z/1)$ where $f_1g_2 - f_2g_1 = \pm 1$, then $U$ is rational.}


Theorems 8 and 10 can  be used when not all the
 knots
involved are  4-plats and are a generalization of [20]  and [21],
respectively.
\vskip -5pt

{\bf Theorem 8 [16]} { If $d_{t/w}(L, N(a/b)) = 1$, then for some  
integer $n$, and $s
\cong w$ mod $t$,
$|H_1({\widetilde{L}})|
\cong < m, L_1 ~|~ tnL_1 + sm, aL_1 - bnm >$.


{\bf Corollary 9}{ If $d_{t/w}(N(a/b), K) = 1$,
then there exists an integer $n$
such that $|H_1(M_K)| \equiv |aw + tbn^2|$ (mod $ta$). }
   
{\bf Theorem 10 [22]} { If $d_{t}(K, K') = 1$, then there exist $a \in    
H_1(M_K)$ and $a' \in H_1(M_{K'})$ such that $\lambda(a, a) \equiv
n/|H_1(M_K)|$ and $\lambda(a', a') \equiv m/|H_1(M_K')|$ (mod 1), where
$$m = n = { \pm 1 \over t}\big ( |H_1(M_K)| - |H_1(M_K')| \big )$$ or
$$-m = n
= { \pm 1 \over t}\big ( |H_1(M_K)| + |H_1(M_K')| \big ) $$ }


Note that theorem 10 also give information regarding ${t
\over kt \pm 1}$ moves since these moves are equivalent to $\pm t$ moves.





{\bf Theorem  { [5]}}{\it \noindent ~Let $U$ and $R$ be tangles such that
$N( U + iR) = $4-plat for some $i \geq 2$, and $N( U + jR) \not= N(U +
iR)$
for some j. Then $R$ is a rational tangle.  If $i \geq 3$, then $R$ is an
integral tangle. }

{\bf Proof [10].}
  
If $R$ were locally knotted, then $N( U + iR), i \geq 2$ would be
composite.  Since 4-plats are prime, $R$ cannot be locally knotted.
Suppose $R$ is a prime tangle. By tangle fact (9) $U + (i-1)R$ is rational
or locally knotted.  By tangle fact (10), $R$ prime implies $(i-1)R$ prime
and $U$ must be the $\infty$-tangle or locally knotted.

Note that $U$ cannot be the $\infty$-tangle.  If $U$ were the infinity
tangle, then $N( U + iR) = D(iR) = D(R) \# ... \# D(R)$.  Since 4-plats 
are prime, $D(R) =$ unknot.  But $N(U + iR) = D(iR) =$ unknot $= D(jR) =
N(U + jR)$, a contradiction.  Thus if $U$ is locally unknotted, $R$ must
be rational.

If $i \geq 3$, then $R$ does not have parity  $\infty$
since 4-plats have at most
two
components.  If $i \geq 3$, $U$ is locally unknotted, and $R$ is not
integral, then if $U$ is not
integral, $U + R$ and $(i-1)R$ are prime by tangle
facts (5) and (10).
But $N( U + iR) = $4-plat would then contradict tangle fact (9).  If
$U$ is integral and if $R$ is rational, then $N( U + iR) = $ 4-plat, $i   
\geq 3$, if and only if $R$ is integral by tangle fact (8).  Thus if
$U$ is locally unknotted and $i \geq 3$, $R$ must
be integral.

Suppose $U$ is locally knotted.  Then if $U'$ is the tangle formed from 
$U$ by removing the local knot, then $N( U' + iR) = $unknot, since 4-plats
are prime.  $N( U + jR) \not= N(U + iR)$ implies that $N( U' + jR) \not=
N(U' + iR)$.  Since the unknot is a 4-plat and $U'$ is locally unknotted,
$R$ is rational if $i \geq 2$ and integral if $i \geq 3$
\,\, \qed\.
 
Cor 6.2:
Solve $N(U + P) = N(1/0)$, $N(U + R) = N(-2/1)$, $N(U + R + R) = N((-2, -1, 
-1)) = N(-5/2)$, \hfil \break
$N(U + R + R + R) = N((-1, -1, -1, -1, -1)) = N(-8/5)$


\end
\eject

\item{[5]}  C. \spa{Ernst}, D. W.  \spa{Sumners}, {\it  A calculus for
rational tangles:  applications to DNA recombination}\/, Math. Proc.
Camb.
Phil. Soc. 108 (1990), 489--515.


\item{[7]} J. R. Goldman, L. H. Kauffman,  {\it Rational
tangles},
Adv.
in
Appl.
Math. 18 (1997), no. 3, 300--332.

\item{[8]} S. Bleiler, {\it Knots prime on many strings}, Trans. Amer.
Math. Soc. 282 (1984), no. 1, 385--401.



\item{[9]} W. B. R. Lickorish, {\it  Prime knots and tangles},
Trans. Amer. Math. Soc.
267 (1981), no. 1,
321--332.

\item{[10]}  C. \spa{Ernst}, D. W.  \spa{Sumners}, {\it
Solving
tangles equations arising in a DNA recombination model}\/, Math.   
Proc. Camb.
Phil. Soc. 124 (1998).

\item{[11]} C. Ernst,  {\it  Tangle equations}, J. Knot Theory
Ramifications 5 (1996), no. 2,
145--159.


\end

\vglue 12pt

